Oxidative Carbon-Carbon Bond Cleavage by Vanadium Catalyst
The aerobic oxidative C?C bond cleavage of vicinal diols catalyzed by vanadium aminotriphenolates is described. Our results show that C?C bond cleavag e can be performed in different solvents,under an air or oxygen atmosphere, with a large variety of glycols (cyclic or linear, with aromati c or aliphaticsubstituents) affording the corresponding carbonyl derivatives with high chemoselectivity.Reactions can be performed with as little as 10 ppm of catalyst reaching TON up to 81,000 and TOFs of up to4150 h?1. A reaction mechanism, rationalized by de nsity functional theory calculations, is also proposed.
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This dataset derived results are published in:
Manuscript title: Efficient Vanadium-Catalyzed Aerobic C?C Bond OxidativeCleavage of Vicinal Diols
Journal: Adv. Synth. Catal.
- 97 DFT
- 96 ADF